90% of Skin Aging is caused by the sun*.

Ultraviolet (UV) radiation from the sun is the #1 cause of skin cancer**
*Skin Cancer Foundation **AmericanCancerSociety.org

An SPF can absorb 92-98% of UV rays, but a portion of rays still penetrate skin.

These rays generate Reactive Oxygen Species [ROS], the root cause of visible skin discoloration and aging. Even with use of sunscreen for protection, most UV filters still generate ROS when exposed to UVA rays.

Ongoing scientific trials

exploring possible future applications of this technology

PROTEXIDINE

Patented antioxidant technology in development to prevent premature aging of the skin

A proprietary biomimetic decoy molecule enhances skin’s innate ability to manage UV induced damage and inhibit Reactive Oxygen Species [ROS], reducing and clearing Cyclobutane Pyrimidine Dimers [CPDs].

ProteXidine

Reduction and Prevention of CPD Formation

Exposure to UV radiation results in the formation of CPDs, markers of UV damage that present as a kink of bend in DNA. Evidence shows with the use of ProteXidine, CPDs are significantly reduced and prevented*.
Untreated Skin
Brown stains [CPDs] indicate damage
Skin Treated with ProteXidine
Prevent formation of CPDs

Untreated Skin

Brown stains [CPDs] indicate damage

Skin Treated with ProteXidine

Prevent formation of CPDs
Brown stains [CPDs] indicate damage
Clear CPDs

Untreated Skin

Brown stains [CPDs] indicate damage

Skin Treated with ProteXidine

Clear CPDs
*Study: ProteXidine UV Protection and UV Damage Repair, University of Minnesota Center for Drug Design. CPDs (brown stains) are significantly reduced.

ProteXidine

Reduction and Prevention of UV Damage

Evidence in human skin explants shows that ProteXidine
increases the clearance of damaged epidermal cells (black arrows) inducing replacement with healthy new cells.
Untreated Skin
Skin Treated with ProteXidine

Untreated Skin

Skin Treated with ProteXidine

Untreated Skin
Skin Treated with ProteXidine

Untreated Skin

Skin Treated with ProteXidine

ProteXidine

Protection against UV Induced Collagen Damage

Collagen loses its basketweave structure due to UV damage. With the use of ProteXidine (a proprietary antioxidant synergist) in clinical trials, collagen is maintained and basketweave structural integrity is preserved.
Untreated Skin
without UV Exposure
Normal collagen with basketweave structure preserved (green)
Untreated Skin
with UV Exposure
Collagen density is reduced with loss of basketweave structure
Skin Treated with ProteXidine
with UV Exposure
Collagen density and basketweave structure is maintained

Educational Series

ProteXidine: A First-in-Class Technology

In the press:
NEWBEAUTY
“A Groundbreaking Molecule in Development Could Overhaul Sunscreen as We Know It”
In the press:
NEWBEAUTY
“A Groundbreaking Molecule in Development Could Overhaul Sunscreen as We Know It”
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